In 2012, Mustafizur travelled to Bangladesh's capital Dhaka to try out for a fast-bowlers camp.Prior to that, scouters first encountered him in an Under-17 tournament in Satkhira. He was admitted to the Bangladesh Cricket Board's foundation of fast bowling. Soon he was selected to the Bangladesh Under-19 side for the 2014 Under-19 Cricket World Cup in UAE, where he took a total of eight wickets. Mustafizur Rahman is a left-arm pace bowler who came to Dhaka to try out for a fast-bowling camp in 2012, after he had impressed in an Under-17 tournament in Satkhira, some 300km from Dhaka. He got admitted to the BCB's pace foundation and soon caught the coaches' attention to make the Bangladesh Under-19 side for the 2014 World Cup. In February 2016, Mustafizur was drafted by Sunrisers Hyderabad in the 2016 IPL auction.He took 17 wickets in 16 matches in the tournament where his team won the title. He was named as "Emerging Player of the Tournament", the first overseas player to receive this award. In December 2016, he was retained by the Sunrisers Hyderabad in the 2017 IPL auction. He was doubtful about missing the first-leg of the tournament. In January 2018, he was bought by the Mumbai Indians in the 2018 IPL auction. In February 2021, he was bought by the Rajasthan Royals from his base price of INR 1.00 crore in the 2021 IPL auction. In February 2022, he was bought by the Delhi Capitals in the auction for the 2022 Indian Premier League tournament. He played 8 match for Delhi capital and took 8 wicket.He currently plays for Indian Premier League team Chennai Super Kings.